Accuracy of Estimated Central Systolic Blood Pressure and Augmentation Index in Patients With Type 2 Diabetes Mellitus

It has been suggested that transfer functions to estimate central aortic systolic blood pressure (SBP) and BP waveform parameters (i.e., augmentation index) may be less accurate in patients with type 2 diabetes mellitus (T2DM). However, these observations have not confirmed a large sample, which was the aim of this study. Consecutive without T2DM undergoing coronary angiography at Royal Hobart Hospital had recorded ascending aorta radial artery fluid-filled catheter. Radial waveforms were processed using SphygmoCor Cardiovascular Management System (CVMS) function (AtCor, Sydney) BP. Two invasive calibration methods used: 1) mean arterial pressure/diastolic (MAP/DBP); 2) SBP DBP (SBP/DBP). between-group analyses performed unadjusted adjusted for age, sex, hypertension, hypercholesterolaemia, body mass index, disease. Data from 64 (61±11 years, 73% male) 186 (62±8 70% analysed. There no difference accuracy estimated between groups when compared MAP/DBP (T2DM –1.8±6 mmHg vs –1.1±5 mmHg; p=0.37; p=0.59) or SBP/DBP –1.2±9 –2.0±9 p=0.57; p=0.66). Augmentation index significantly different 0.8±12% 3.7±14%; p=0.13, respectively). Estimated do appear are calibrated